Research Engineer, Ecole Polytechnique
Room: 84-20-17
Phone: (+33) 1 69 33 50 63
Nous contacter

ORCID ID : 0000-0003-4452-1011
Google scholar profile

Current projects:

Management of the imaging facility Morphoscope: Formation and scientific counselling of microscope users, maintenance and upgrade of commercial systems

Optical design and set-up implementation for multiphoton microscopy: Two-photon Light-Sheet microscopy, Three-photon point scanning microscopy and Serial Two-photon tomography

For more details see our group webpage: Advanced microscopies & tissue physiology

Background:

2015-Present: Research engineer at Laboratory for Optics and Biosciences (Ecole Polytechnique, France)

2013-2015: Post-doctoral researcher at Laser Analytics Group (University of Cambridge, UK)

2013: Post-doctoral researcher at Laboratory for Optics and Biosciences (Ecole Polytechnique, France)

2009-2012: PhD in Biophysics at Laboratory for Optics and Biosciences (Ecole Polytechnique, France),

Title: Nonlinear microscopy of biological tissues: multicolor excitation, Bessel beams and light sheet microscopy

Thesis Advisors: Dr. Emmanuel Beaurepaire and Dr. Delphine Débarre

Teaching:

Since 2019: In charge of the M2 Lecture "Impulsions Optiques Ultrabrèves et leurs Applications"

Publications:

Full list on my Google Scholar profile

Selected publications:

Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
N. Dray, L. Mancini, U. Binshtok, F. Cheysson, W. Supatto, P. Mahou, S. Bedu, S. Ortica, M. Krecsmarik, S. Herbert, J.-B. Masson, J.-Y. Tinevez, G. Lang, E. Beaurepaire, D. Sprinzak, L. Bally-Cuif,
Cell Stem Cell (2021)

Fast In Vivo Imaging of SHG Nanoprobes with Multiphoton Light-Sheet Microscopy
G. Malkinson, P. Mahou, E. Chaudan, T. Gacoin, A. Y Sonay, P. Pantazis, E. Beaurepaire, W. Supatto,
ACS Photonics (2020)

Fast in vivo multiphoton light-sheet microscopy with optimal pulse frequency
V. Maioli, A. Boniface, P. Mahou, J. Ferrer Ortas, L. Abdeladim, E. Beaurepaire, W. Supatto,
Biomedical Optics Express (2020)

Multicolor multiscale brain imaging with chromatic multiphoton serial microscopy
L. Abdeladim, K. S. Matho, S. Clavreul, P. Mahou, J.-M. Sintes, X. Solinas, I. Arganda-Carreras, S. G. Turney, J. W. Lichtman, A. Chessel, A.-P. Bemelmans, K. Loulier, W. Supatto, J. Livet, E. Beaurepaire,
Nature Communications (2019)

An actin-based viscoplastic lock ensures progressive body-axis elongation
A. Lardennois, G. Pásti, T. Ferraro, F. Llense, P. Mahou, J. Pontabry, D. Rodriguez, S. Kim, S. Ono, E. Beaurepaire, C. Gally, M. Labouesse,
Nature (2019)

Snapshots of archaeal DNA replication and repair in living cells using super-resolution imaging
F. Delpech, Y. Collien, P. Mahou, E. Beaurepaire, H. Myllykallio, R. Lestini
Nucleic Acids Research (2018)

Dual-color deep-tissue three-photon microscopy with a multiband infrared laser
K. Guesmi, L. Abdeladim, S. Tozer, P. Mahou, T. Kumamoto, K. Jurkus, P. Rigaud, K. Loulier, N. Dray, P. Georges, M. Hanna, J. Livet, W. Supatto, E. Beaurepaire, F. Druon
Light Science & Applications (2018)

Metrology of Multiphoton Microscopes Using Second Harmonic Generation Nanoprobes
P. Mahou, G. Malkinson, É. Chaudan, T. Gacoin, E. Beaurepaire, W. Supatto
Small  (2017)

Multicolor two-photon light-sheet microscopy
P. Mahou, J. Vermot, E. Beaurepaire & W. Supatto
Nature Methods (2014)

Multicolor two-photon tissue imaging by wavelength mixing
P. Mahou, M.S. Zimmerley, K. Loulier, K.S. Matho, G. Labroille, X. Morin, W. Supatto, J. Livet, D. Débarre & E. Beaurepaire 
Nature Methods (2012)