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Pascale Changenet

CNRS researcher
Laboratoire d'Optique et Biosciences
CNRS UMR 7640 -INSERM U1182 - Ecole Polytechnique
91128 Palaiseau, Cedex, France

Room: 02-2015
Tel: (+33) 169 335 030
e-mail: Nous contacter

 
 
 

Research interests:

Light-induced processes in complex molecular systems.
DNA G-quadruplex structures and folding dynamics.
Time-resolved circular dichroism and femtosecond transient absorption spectroscopy.


Positions:

Since 2014: CNRS research position, Laboratoire d’Optique et Biosciences, UMR 7645, Ecole Polytechnique, Palaiseau.
2010-2014: CNRS research position, Laboratoire Francis Perrin URA 2453, CEA/Saclay.
2000-2010: CNRS research position, Département de Chimie UMR 8640, ENS, Paris.
1998-2000: CNRS research position, Laboratoire de Photophysique Moléculaire UPR 3361, University of Paris XI, Orsay.


Teaching:

Since 2011: Ultrafast spectroscopy, Master 2 PCCPM and Erasmus mundus SERP−Chem, University of Paris XI, Orsay.
2008−2011: Photochemistry, Master 1 Chemistry ENS−UPMC, ENS−Paris.
2005−2008: Ultrafast spectrocopy, Master 2 Physico−Chimie Moléculaire, University of Paris XI, Orsay.


Education:

2011: HdR, University of Paris XI, Orsay.
1997-1998: Post-doc, University of Pennsylvania, USA.
1996-1997: Post-doc, University of Amsterdam, The Netherlands.
1993-1996: PhD, Laboratoire de Photophysique Moléculaire, University of Paris XI, Orsay.
1992-1993: Diploma thesis on Chemical Physics, University of Paris XI, Orsay.


Awards:

CNRS Bronze medal in 2002


Selected publications:

Ultrafast Electron Transfer in Complexes of Doxorubicin with Human Telomeric G-Quadruplexes and GC Duplexes Probed by Femtosecond Fluorescence Spectroscopy
P. Changenet-Barret, T. Gustavsson, D. Markovitsi, I. Manet, CHEMPHYSCHEM (2016) 17, 1264-1272.

Ultrafast Excited-State Deactivation of 8-Hydroxy-2 '-deoxyguanosine Studied by Femtosecond Fluorescence Spectroscopy and Quantum-Chemical Calculations
P. Changenet-Barret, T. Gustavsson, R. Improta, D. Markovitisi, Journal of Physical Chemistry A (2015) 119, 6131-6139.

Electronic Excitations in Guanine Quadruplexes
P. Changenet-Barret, Y. Hua, D. Markovitsi, Topics in Current Chemistry (2015) 356, 183-201

Ultrafast Carbonyl Motion of the Photoactive Yellow Protein Chromophore Probed by Femtosecond Circular Dichroism
L. Mendonca, F. Hache, P. Changenet-Barret, P. Plaza, H. Chosrowjan, S. Taniguchi, Y. Imamoto, Journal of the American Chemical Society (2013) 135, 14637-14643

The effect of size on the optical properties of guanine nanostructures: a femtosecond to nanosecond study
Y. Hua, P. Changenet-Barret, T. Gustavsson, D. Markovitsi, Physical Chemistry Chemical Physics (2013) 15, 7396-7402

Unravelling molecular mechanisms in the fluorescence spectra of doxorubicin in aqueous solution by femtosecond fluorescence spectroscopy
P. Changenet-Barret, T. Gustavsson, D. Markovitsi, I. Manet, S. Monti, Physical Chemistry Chemical Physics (2013) 15, 2937-2944

Optical Properties of Guanine Nanowires: Experimental and Theoretical Study
P. Changenet-Barret, E. Emanuele, T. Gustavsson, R. Improta, A. B. Kotlyar, D. Markovitsi, I. Vaya, K. Zakrzewska, D. Zikich, Journal of Physical Chemistry C (2010) 114, 14339-14346

Primary photodynamics of a biomimetic model of photoactive yellow protein (PYP)
P. Changenet-Barret, C. Loukou, C. Ley, F. Lacombat, P. Plaza, J.-M. Mallet, M. M. Martin, Physical Chemistry Chemical Physics (2010) 12, 13715-13723

Structural effects on the photoisomerization of PYP probed by ultrafast absorption spectroscopy of two point mutants
P. Changenet-Barret, P. Plaza, M. M. Martin, H. Chosrowjan, S. Taniguchi, N. Mataga, Y. Imamoto, M. Kataoka, Journal of Physical Chemistry C (2009) 113, 11605-11613