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Chiara Stringari

Research scientist - CNRS
Room: 84-2017, 05-2016A
Phone: (+33) 1 69 33 5021

chiara.stringari at polytechnique.edu

Current research activity:
Advanced microscopies & tissue physiology                                          



2014-present: Research scientist (CR1 CNRS), Lab. for optics and biosciences, Ecole Polytechnique, Palaiseau.

2013-2014: Postdoc, Lab. for optics and biosciences, Ecole Polytechnique, Palaiseau. (Dr. E. Beaurepaire)

2009-2013: Postdoctoral Fellow - Core Group Leader Laboratory for Fluorescence Dynamics, Department of Biomedical Engineering, University of California, Irvine. (Dr. E. Gratton)

2005-2008 PhD, Biophysics and Biophotonics Lab, European Laboratory for Non-Linear Spectroscopy (Dr. F.S. Pavone)



Selected publications:

High-speed polarization-resolved third-harmonic microscopy  J. Morizet, G. Ducourthial, W. Supatto, A. Boutillon, R. Legouis, M.-C. Schanne-Klein, C. Stringari, E. Beaurepaire Optica 6 (3), 385-388 (2019)

Multicolor two-photon imaging of endogenous fluorophores in living tissues by wavelength mixing Stringari C., Abdeladim L., Malkinson G., Mahou P., Solinas X., Lamarre I., Brizion S., Galey J.B, Supatto W., Legouis R., Pena A.M., Beaurepaire E. Sci. Rep. 7(1):3792. (2017)

Spatial dynamics of SIRT1 dictate metabolic transitions in the cell nucleus. Aguilar-Arnal L.*, Ranjit S.*, Stringari C., Orozco-Solis R., Gratton E., Sassone-Corsi P. Proceedings of the National Academy of Sciences U S A  (2016)

Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells. Borrego S., Fahrmann J., Datta. R., Stringari C., Grapov D., Zeller M. Baldi P., Gratton. E., Keiser P.  Cancer & Metabolism 2;4:9 (2016)

NADH fluorescence lifetime is an endogenous reporter of alpha-synuclein aggregation in live cells, Plotegher N., Stringari C, Jahid S., Veronesi M. , Girotto S., Gratton E., Bubacco L. FASEB J. 29(6):2484-94 (2015).

In Vivo single-cell detection of metabolic oscillations in stem cells. Stringari C, Wang H, Geyfman M, Crosignani V, Kumar V, Takahashi JS, Andersen B, Gratton E.  Cell Rep. 10(1):1-7 (2015).

Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. Pate K.T., Stringari C., Sprowl-Tanio S., Wang K., TeSlaa T., Hoverter N.P., McQuade M.M., Garner C., Digman M.A., Teitell M.A., Edwards R.A., Gratton E., Waterman M.L.  EMBO J. 33(13):1454-73 (2014)

Two-photon excited fluorescence life-time, spectroscopy and imaging of melanins in-vitro and in-vivo. Krasieva T.B., Stringari C., Liu F., Sun C.H., Kong Y., Balu M., Meyskens F.L., Gratton E., and Tromberg B.J. J Biomed Opt.18(3):31107 (2013)

Metabolic trajectory associated with cellular proliferation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH, Stringari C., Edwards RA, Pate KT, Waterman ML, Donovan PJ, Gratton E.  Sci. Rep. 2:568 (2012)

Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue. Stringari C., Cinquin A., Cinquin O., Digman MA., Donovan P., Gratton E. Proceedings of the National Academy of Sciences U S A 108(33):13582-13587 (2011)

Probing myosin structural conformation in vivo by second-harmonic generation microscopy Nucciotti* V., Stringari* C., Sacconi* L., Vanzi* F., Fusi L., Linari M., Piazzesi G., Lombardi V.  Pavone F.S.  Proceedings of the National Academy of Sciences U S A 107(17):7763-8 (2010)

Full list on google scholar