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Whole-brain functional imaging in zebrafish larvae

Researchers from the Laboratoire Jean Perrin (LJP, CNRS/UPMC, Paris) and the Laboratoire d’optique et biosciences (LOB, CNRS/Polytechnique/Inserm, Palaiseau) have shown that two-photon light-sheet microscopy makes it possible to study brain-wide activity with cellular resolution in zebrafish larvae in response to visual stimulations.

Reference:
Whole-brain functional imaging with two-photon light-sheet microscopy
S. Wolf, W. Supatto, G. Debrégeas, P. Mahou, S. Kruglik, J.-M. Sintes, E. Beaurepaire, R. Candelier
Nature Methods  12, 379 (2015)