Publications
Recent publications :
- Gabel F, Engilberge S, Schmitt E, Thureau A, Mechulam Y, Pérez J, Girard E. Medical contrast agents as promising tools for biomacromolecular SAXS experiments. Acta Crystallogr D Struct Biol, 2022, 78, 1120-1130, doi.org/10.1107/S2059798322007392.
- Kazan R, Bourgeois G, Carisetti D, Florea I, Larquet E, Maurice JL, Mechulam Y, Ozanam F, Schmitt E, Coureux PD. Grid batch-dependent tuning of glow discharge parameters. Front Mol Biosci. 2022, 18;9:910218, doi.org/10.3389/fmolb.2022.910218.
- Kazan R, Bourgeois G, Lazennec-Schurdevin C, Larquet E, Mechulam Y, Coureux PD, Schmitt E. Role of aIF5B in archaeal translation initiation. Nucleic Acids Res. 2022, 50, 6532–6548, doi.org/10.1093/nar/gkac490.
- Das P, Ngo KH, Winnerdy FR, Maity A, Bakalar B, Mechulam Y, Schmitt E, Phan AT. Bulges in left-handed G-quadruplexes. Nucleic Acids Res. 2021 Feb 22;49(3):1724-1736, doi.org/10.1093/nar/gkaa1259.
- Bourgeois G, Seguin J, Babin M, Gondry M, Mechulam Y, Schmitt E. Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates. RNA. 2020 Jul 17:rna.075184.120, doi.org/10.1261/rna.075184.120.
- Schmitt, E, Coureux, P-D, Kazan, R., Bourgeois, G., Lazennec-Schurdevin, C., Mechulam, Y. Recent advances in archaeal translation initiation. Frontiers in Microbiology, section Biology of Archaea. (invited review) Front Microbiol. 2020 Sep 18;11:584152, doi.org/10.3389/fmicb.2020.584152.
- Coureux PD, Lazennec-Schurdevin C, Bourcier S, Mechulam Y, Schmitt E.Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Commun Biol. (2020) Feb 6;3(1):58, doi.org/10.1038/s42003-020-0780-0. - Opuu V, Nigro G, Gaillard T, Schmitt E, Mechulam Y, Simonson T.Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power. PLoS Comput Biol. (2020) Jan 9;16(1):e1007600, doi.org/10.1371/journal.pcbi.1007600. eCollection 2020 Jan.
- Nigro G, Bourcier S, Lazennec-Schurdevin C, Schmitt E, Marlière P, Mechulam Y.Use of β3-methionine as an amino acid substrate of Escherichia coli methionyl-tRNA synthetase. J Struct Biol. (2019) Dec 17:107435, doi.org/10.1016/j.jsb.2019.107435.
- Heddi B, Cheong VV, Schmitt E, Mechulam Y, Phan AT. Recognition of different base tetrads by RHAU: X-ray crystal structure of the G4 recognition motif bound to the 3’-end tetrad of a DNA G-quadruplex. Journal of Structural Biology, Elsevier, (2019), pp.S1047-8477(19)30210-2, doi.org/10.1016/j.jsb.2019.10.001.
- Winnerdy FR, Bakalar B, Maity A, Vandana JJ, Mechulam Y, Schmitt E, Phan AT. NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., (2019), pp.gkz349, doi.org/10.1093/nar/gkz349.
- Bakalar B, Heddi B, Schmitt E, Mechulam Y, Phan AT. A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew Chem Int Ed Engl. (2019) Nov 27, doi.org/10.1002/anie.201812628.
- Monestier A, Lazennec-Schurdevin C, Coureux PD, Mechulam Y, Schmitt E. Role of aIF1 in Pyrococcus abyssi translation initiation. Nucleic Acids Res. (2018), doi.org/10.1093/nar/gky850.
- Schmitt E, Bourgeois G, Gondry M, Aleksandrov A. Cyclization Reaction Catalyzed by Cyclodipeptide Synthases Relies on a Conserved Tyrosine Residue. Sci Rep. (2018), doi.org/10.1038/s41598-018-25479-5.
- Visweshwaran SP, Thomason PA, Guerois R, Vacher S, Denisov EV, Tashireva LA, Lomakina ME, Lazennec-Schurdevin, C, Lakisic G, Lilla S, Molinie N, Henriot V, Mechulam Y, Crews CM, Alexandrova AY, Perelmuter VM, Cherdyntseva NV, Bièche I, Schmitt E, Insall RH, Gautreau A. A trimeric coiled coil protein promotes WASH complex assembly. EMBO J. (2018), doi.org/10.15252/embj.201797706.
- Bourgeois G, Seguin J, Babin M, Belin P, Moutiez M, Mechulam Y, Gondry M and Schmitt E. Structural basis for partition of the cyclodipeptide synthases into two subfamilies. J. Struct. Biol. (2018) 203:17-26, doi.org/10.1016/j.jsb.2018.03.001.
- Monestier A, Aleksandrov A, Coureux PD, Panvert M, Mechulam Y, Schmitt E. The structure of an E. coli tRNAfMet A1-U72 variant shows an unusual conformation of the A1-U72 base pair. RNA. (2017), doi.org/10.1261/rna.057877.116.
- Coureux PD, Lazennec-Schurdevin C, Monestier A, Larquet E, Cladière L, Klaholz BP, Schmitt E, Mechulam Y. (2016) Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun. 7:13366, doi.org/10.1038/ncomms13366.